Pinky and the Brain is a beloved animated series that masterfully blends comedy and science fiction. If you’re a fan of the misadventures of these two lab mice, you’re in for a treat! Here are 19 TV shows that capture the same spirit of humor, intelligence, and quirky characters. Check out the list below and find your next binge-worthy series.
1. Animaniacs
“Animaniacs” is a zany, animated show featuring the Warner siblings—Yakko, Wakko, and Dot—along with a variety of other memorable characters. The show is known for its clever humor, musical numbers, and pop culture references. It stars Rob Paulsen, Jess Harnell, and Tress MacNeille.
2. Futurama
“Futurama” is a science fiction comedy from the creators of “The Simpsons.” The show follows Fry, a pizza delivery boy who wakes up 1,000 years in the future, and his adventures with a motley crew of friends. It stars Billy West, Katey Sagal, and John DiMaggio.
3. Rick and Morty
“Rick and Morty” is an adult animated series that blends science fiction with dark humor. The show follows the misadventures of an eccentric scientist, Rick, and his good-hearted but easily influenced grandson, Morty. It stars Justin Roiland and Chris Parnell.
4. The Simpsons
“The Simpsons” is a long-running animated sitcom that offers a satirical look at the American family. The show features the Simpson family—Homer, Marge, Bart, Lisa, and Maggie—and their interactions with the residents of Springfield. It stars Dan Castellaneta, Julie Kavner, and Nancy Cartwright.
5. Dexter’s Laboratory
“Dexter’s Laboratory” is an animated series about a boy-genius named Dexter who has a secret lab filled with inventions. His experiments are often thwarted by his pesky sister, Dee Dee. The show stars Christine Cavanaugh and Kat Cressida.
6. The Ren & Stimpy Show
“The Ren & Stimpy Show” is a surreal and often controversial cartoon that follows the antics of Ren, a neurotic chihuahua, and Stimpy, a dim-witted cat. The show is known for its dark humor and unique animation style. It stars John Kricfalusi and Billy West.
7. Invader Zim
“Invader Zim” is an animated series that follows Zim, an alien invader who is trying to conquer Earth, and his malfunctioning robot sidekick, GIR. The show is known for its dark humor and unique art style. It stars Richard Steven Horvitz and Rosearik Rikki Simons.
8. Phineas and Ferb
“Phineas and Ferb” is an animated series about two stepbrothers who embark on imaginative and elaborate adventures during their summer vacation. Their pet platypus, Perry, leads a double life as a secret agent. The show stars Vincent Martella and Ashley Tisdale.
9. Gravity Falls
“Gravity Falls” is a mystery-comedy series that follows twins Dipper and Mabel Pines as they spend the summer with their great-uncle Stan in the mysterious town of Gravity Falls. The show is known for its clever writing and engaging plot. It stars Jason Ritter and Kristen Schaal.
10. The Fairly OddParents
“The Fairly OddParents” is an animated series about a young boy named Timmy Turner who is granted two fairy godparents, Cosmo and Wanda, who can grant his every wish. The show is full of humor and magical adventures. It stars Tara Strong and Daran Norris.
11. Teen Titans Go!
“Teen Titans Go!” is a comedic take on the popular Teen Titans superhero team, focusing on their everyday lives and humorous adventures. The show features a mix of action and comedy. It stars Greg Cipes, Scott Menville, and Khary Payton.
12. Adventure Time
“Adventure Time” is an animated series that follows Finn the Human and his best friend Jake the Dog as they embark on surreal and magical adventures in the Land of Ooo. The show is known for its creativity and emotional depth. It stars Jeremy Shada and John DiMaggio.
13. The Amazing World of Gumball
“The Amazing World of Gumball” is an animated series that follows the misadventures of Gumball Watterson and his family in the fictional city of Elmore. The show is known for its unique animation style and witty humor. It stars Nicolas Cantu and Donielle T. Hansley Jr.
14. Johnny Bravo
“Johnny Bravo” is an animated comedy series that follows the titular character, a muscular and dim-witted man who constantly tries to impress women. The show is known for its slapstick humor and pop culture references. It stars Jeff Bennett and Brenda Vaccaro.
15. Samurai Jack
“Samurai Jack” is an animated series that follows a samurai named Jack who is sent to a dystopian future by the evil shape-shifting demon, Aku. The show is known for its stunning visuals and epic storytelling. It stars Phil LaMarr and Mako Iwamatsu.
16. Courage the Cowardly Dog
“Courage the Cowardly Dog” is an animated horror-comedy series that follows a timid dog named Courage who must protect his elderly owners from supernatural threats. The show is known for its dark humor and eerie atmosphere. It stars Marty Grabstein and Thea White.
17. The Powerpuff Girls
“The Powerpuff Girls” is an animated series that follows three super-powered sisters—Blossom, Bubbles, and Buttercup—as they protect their city from various villains. The show is known for its action-packed episodes and colorful animation. It stars Cathy Cavadini, Tara Strong, and E.G. Daily.
18. SpongeBob SquarePants
“SpongeBob SquarePants” is an animated series that follows the underwater adventures of SpongeBob and his friends in the fictional city of Bikini Bottom. The show is known for its humor and quirky characters. It stars Tom Kenny, Bill Fagerbakke, and Rodger Bumpass.
19. BoJack Horseman
“BoJack Horseman” is an adult animated series that follows the life of BoJack, a washed-up actor who happens to be a horse, as he navigates the ups and downs of Hollywood. The show is known for its dark humor and emotional depth. It stars Will Arnett, Amy Sedaris, and Alison Brie.
Enjoy exploring these fantastic TV shows that capture the same magic as Pinky and the Brain!
